Introduction to Southern Brisket Grilled Cheese There’s something magical about a grilled cheese sandwich, isn’t there? Now, imagine that classic comfort food, but with a Southern twist. The Southern Brisket Grilled Cheese is not just a meal; it’s a warm hug on a plate. Whether you’re racing against the clock after a long day or looking to impress friends at a weekend gathering, this recipe is your go-to. With smoky brisket and sharp cheddar nestled between crispy sourdough, it’s a hearty delight that satisfies both hunger and nostalgia. Let’s dive into this delicious adventure together! Why You’ll Love This Southern Brisket Grilled Cheese This Southern Brisket Grilled Cheese is a game-changer for busy days. It’s quick to whip up, taking just 18 minutes from start to finish. The combination of smoky brisket and sharp cheddar creates a flavor explosion that’s hard to resist. Plus, it’s a fantastic way to use leftover brisket, turning it into a comforting meal that feels gourmet. Trust me, your taste buds will thank you! Ingredients Southern Brisket Grilled Cheese Creating the perfect Southern Brisket Grilled Cheese starts with quality ingredients. Here’s what you’ll need: Sourdough bread: This bread adds a delightful crunch and tangy flavor. It’s sturdy enough to hold all the delicious fillings. Smoked brisket: The star of the show! Tender, smoky, and packed with flavor, it elevates this sandwich to new heights. Sharp cheddar cheese: This cheese brings a bold, rich taste that perfectly complements the brisket. It melts beautifully, creating that gooey goodness we all crave. Barbecue sauce: A drizzle of your favorite BBQ sauce adds a sweet and tangy kick. It’s the secret ingredient that ties everything together. Unsalted butter: For that golden, crispy exterior, butter is essential. It adds richness and flavor to the sandwich. Mayonnaise: This creamy spread enhances the sandwich’s moisture and flavor. It’s a game-changer for grilled cheese! Worcestershire sauce: Just a dash adds depth and umami, making your sandwich even more irresistible. Salt and pepper: Simple seasonings that enhance the overall flavor. Don’t skip these! Feel free to get creative! For a spicy kick, consider adding sliced jalapeños inside the sandwich. And if you want to make it a complete meal, serve it with a side of coleslaw or pickles. Exact quantities for each ingredient are available at the bottom of the article for easy printing. How to Make Southern Brisket Grilled Cheese Making a Southern Brisket Grilled Cheese is a straightforward process that yields delicious results. Follow these simple steps, and you’ll have a mouthwatering sandwich ready in no time! Step 1: Preheat the Skillet Start by preheating your skillet over medium heat. This ensures that your sandwich cooks evenly and gets that perfect golden crust. A hot skillet is key to achieving that crispy exterior we all love! Step 2: Prepare the Spread In a small bowl, mix together mayonnaise, Worcestershire sauce, salt, and pepper. This creamy spread adds moisture and flavor to your sandwich. Spread this mixture generously on one side of each slice of sourdough bread. Trust me, it makes a world of difference! Step 3: Assemble the Sandwich Now, let’s build this beauty! On the unspread side of one slice, layer the shredded smoked brisket. Drizzle some barbecue sauce over the brisket, then add the sharp cheddar cheese. Top it off with the second slice of bread, spread side up. This combination is where the magic happens! Step 4: Cook the Sandwich Melt the unsalted butter in your preheated skillet. Carefully place the assembled sandwich in the skillet. Cook for about 3-4 minutes until the bottom is golden brown. Then, flip the sandwich and cook for another 3-4 minutes. You want the cheese to melt and the other side to be just as golden. Keep an eye on it; nobody likes a burnt sandwich! Step 5: Serve and Enjoy Once cooked, remove the sandwich from the skillet and let it cool for a minute. This helps the cheese set a bit, making it easier to slice. Cut it in half, and serve it warm. Pair it with coleslaw or pickles for a complete meal. Enjoy every gooey, smoky bite of your Southern Brisket Grilled Cheese! Tips for Success Use fresh sourdough for the best texture and flavor. Don’t rush the cooking process; a medium heat ensures even melting. Experiment with different cheeses for unique flavor profiles. Let the sandwich rest before slicing to keep the cheese from oozing out. For extra crunch, grill the sandwich in a cast-iron skillet. Equipment Needed Skillet: A non-stick skillet works well, but a cast-iron skillet gives that extra crunch. Spatula: A sturdy spatula is essential for flipping your sandwich without losing any fillings. Mixing bowl: Any small bowl will do for mixing your spread. Knife: A sharp knife is needed for slicing the sandwich once it’s cooked. Variations Spicy Southern Brisket Grilled Cheese: Add sliced jalapeños or a sprinkle of crushed red pepper flakes for a fiery kick. Vegetarian Option: Swap the brisket for grilled vegetables like zucchini, bell peppers, and mushrooms for a hearty, meatless version. Cheesy Delight: Mix in a blend of cheeses, such as pepper jack or gouda, for a richer flavor profile. BBQ Pulled Pork: Substitute smoked brisket with pulled pork for a different Southern classic. Gluten-Free Version: Use gluten-free bread to make this delicious sandwich suitable for those with dietary restrictions. Serving Suggestions Coleslaw: A tangy coleslaw pairs perfectly, adding crunch and freshness to your meal. Pickles: Serve with dill pickles for a zesty contrast to the rich flavors of the sandwich. Sweet Tea: A glass of sweet tea complements the Southern vibe and balances the savory elements. Presentation: Cut the sandwich diagonally and serve on a rustic wooden board for a charming touch. FAQs about Southern Brisket Grilled Cheese Can I use leftover brisket for this recipe? Absolutely! Leftover brisket is perfect for this Southern Brisket Grilled Cheese. It adds that smoky flavor and makes the sandwich even more satisfying. What type of cheese works best? While sharp cheddar is a classic choice, feel free to experiment! Pepper jack or gouda can add a unique twist to your grilled cheese experience. How do I store leftovers? If you have any leftovers, store them in an airtight container in the fridge. Reheat in a skillet for the best results, ensuring the cheese melts nicely again. Can I make this sandwich ahead of time? While it’s best enjoyed fresh, you can prepare the ingredients ahead of time. Assemble the sandwich and store it in the fridge until you’re ready to cook. Is this Southern Brisket Grilled Cheese gluten-free? To make it gluten-free, simply use gluten-free bread. The rest of the ingredients are naturally gluten-free, so you can enjoy this delicious sandwich without worry! Final Thoughts Every bite of the Southern Brisket Grilled Cheese is a celebration of flavors and memories. It’s more than just a sandwich; it’s a comforting reminder of family gatherings and backyard barbecues. The smoky brisket, sharp cheddar, and crispy sourdough come together to create a dish that warms the soul. Whether you’re enjoying it solo or sharing it with loved ones, this recipe brings joy to the table. So, fire up that skillet and treat yourself to a delightful experience that’s sure to become a favorite in your kitchen. You deserve it! Stephanie Southern Brisket Grilled Cheese: A Must-Try Delight! A delicious Southern-style grilled cheese sandwich featuring smoked brisket and sharp cheddar cheese, perfect for a hearty meal. Print Recipe Prep Time 10 minutes minsCook Time 8 minutes minsTotal Time 18 minutes mins Servings: 1 servingCourse: SandwichCuisine: SouthernCalories: 550 Ingredients Method Nutrition Notes Ingredients 1x2x3x? 2 slices of sourdough bread2 ounces smoked brisket shredded2 slices sharp cheddar cheese2 tablespoons barbecue sauce1 tablespoon unsalted butter1 tablespoon mayonnaise1 teaspoon Worcestershire sauceSalt and pepper to taste Method Preheat a skillet over medium heat.In a small bowl, mix the mayonnaise, Worcestershire sauce, salt, and pepper. Spread this mixture on one side of each slice of sourdough bread.On the unspread side of one slice, layer the shredded brisket, barbecue sauce, and cheddar cheese. Top with the second slice of bread, spread side up.Melt the butter in the preheated skillet. Carefully place the sandwich in the skillet. Cook for about 3-4 minutes until the bottom is golden brown.Flip the sandwich and cook for an additional 3-4 minutes until the cheese is melted and the other side is golden brown.Remove from the skillet, let it cool for a minute, then slice in half and serve. Nutrition Serving: 1sandwichCalories: 550kcalCarbohydrates: 30gProtein: 30gFat: 35gSaturated Fat: 20gPolyunsaturated Fat: 10gCholesterol: 100mgSodium: 800mgFiber: 2gSugar: 5g Notes For a spicy kick, add sliced jalapeños inside the sandwich. To make it a complete meal, serve with a side of coleslaw or pickles. Tried this recipe?Let us know how it was!