In a large mixing bowl, combine ground turkey, panko breadcrumbs, red onion, green bell pepper, corn, smoked paprika, cumin, onion powder, sea salt, black pepper, and crushed red pepper flakes. Mix gently with your hands.
Portion the mixture into four equal parts and shape each into a thick patty, about 3/4 inch thick.
Heat avocado oil in a large skillet over medium heat. Once shimmering, add the patties to the skillet.
Cook the patties for about 5-6 minutes on each side, or until they reach an internal temperature of 165°F and are golden brown.
While the patties cook, place the burger buns cut-side down in the skillet for 1-2 minutes until toasted and lightly browned.
To serve, layer each toasted bun with a turkey patty, add avocado slices, and top with salsa. Garnish with chopped cilantro if desired.